What we do

• Real-world evidence (RWE) generation through the analysis of healthcare databases (e.g., administrative claims databases, general practitioner and pediatrician databases), under specific data-sharing agreements, for pharmacoepidemiology, pharmacovigilance, and post-authorisation safety studies (PASS);
• Systematic literature reviews and meta-analyses to support clinical research, health technology assessment (HTA), and regulatory submissions;
• Review of pharmaceutical innovation dossiers, including the critical appraisal of evidence submitted for innovative medicine assessment and the preparation of concise technical reports summarizing the outcomes of the review;
• Development of predictive algorithms based on artificial intelligence and machine learning for disease identification (particularly rare diseases), and prediction of treatment response.

INSPIRE supports hospitals and local health authorities (LHUs) by:

• Designing and developing electronic Case Report Forms (eCRFs) and study databases for clinical and observational research;
• Coordinating ad hoc data collection activities;
• Performing statistical analyses and producing scientific and technical reports to support clinical research and healthcare decision-making.

INSPIRE provides scientific consultancy to Local Health Authorities (LHUs), Regional Health Services, and other healthcare organizations by developing and periodically monitoring process and outcome indicators based on routinely collected healthcare data. These activities support healthcare planning and performance evaluation by:

• Monitoring the quality and appropriateness of healthcare services;
• Assessing clinical outcomes in patients with chronic diseases;
• Optimizing therapeutic pathways and medication use;
• Supporting evidence-based healthcare management;
• Reducing healthcare risks, resource utilization, and associated costs while improving patient outcomes.